Prolapse of the mitral valve: clinical and cine-angiocardiographic findings.

Mitral regurgitation can result from a variety of anatomical and functional abnormalities and can be the consequence ofseveral disease processes. Clinical recognition of the etiology is most often based on the history, while the functional anatomy of the lesion can occasionally be predicted by certain auscultatory findings. This paper describes a unique anatomical type of mitral regurgitation, recognized cine-angiographically, which occurs in association with a murmur in the latter part of systole or marked accentuation of a soft holosystolic murmur in late systole. Correlations of the cine-angiograms with phonocardiograms have provided a functional anatomical basis for the late onset of the murmur as well as the systolic click which was present in 3 of the patients.